Senior/Executive Director Clinical Research Physician - Breast Cancer/PI3K

Company: Eli Lilly and Company
Location: Indianapolis
Posted on: February 12, 2026

Job Description:

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing, and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but we also develop creative solutions to support communities through philanthropy and volunteerism. For more than 50 years, Lilly Oncology has been delivering life-changing medicines and support to people living with cancer and those who care for them. Our oncology global medical affairs team seeks to understand, generate, and share key data, science, and insights in order to deliver improved outcomes for cancer patients. The clinical research physician (CRP) in Lilly Oncology’s Global Medical Affairs organization will help accelerate the impact we can have on patient lives across the globe. Through the application of scientific and medical training, clinical expertise, and relevant experience, the Global Medical Affairs CRP is an integral member our medical team supporting strategic planning, drug development, and commercialization activities with the goal of improving outcomes for those with cancer. This CRP role focuses on breast cancer, primarily supporting the activities associated with tersolisib, a selective PI3Ki currently in late-phase development. Primary Responsibilities: This job description is intended to provide a general overview of the job requirements at the time it was prepared. The job requirements of any position may change over time and may include additional responsibilities not specifically described in the job description. Consult with your supervisor / hiring manager regarding your actual job responsibilities and any related duties that may be required for the position. The primary responsibility of the Global Medical Affairs CRP is to provide expert medical and scientific support to all aspects of the business, to ultimately improve outcomes for those with cancer. This includes support for drugs in development, marketed products, and the disease state. The CRP leverages deep scientific and clinical expertise to formulate meaningful and compelling clinical and scientific narratives, engage with external stakeholders, and identify evidence gaps that inform strategic priorities. By synthesizing insights from the therapeutic landscape and healthcare provider needs, the CRP plays a critical role in shaping the scientific strategy and ensuring impactful dissemination of data. The core job responsibilities may include those listed below as well as other duties as assigned. Key Competencies for Success in This Role : Leadership & Strategic Execution : · Demonstrated track record of leading and developing high-performing teams (experience managing 3-4 direct reports preferred) · Proven ability to translate strategic vision into actionable plans with measurable outcomes and drive consistent implementation · Strong project management oversight with track record of delivering against timelines and objectives · Experience leading cross-functional initiatives from conception through successful execution Therapeutic Area, Product Expertise and Strategy Development: · Breast cancer tumor expertise strongly preferred · Experience with drugs targeting PI3K-AKT-mTOR pathway preferred (pre-launch, launch and/or post-launch experience) · Pre-launch experience highly valued, including disease education, clinical trial awareness, and product positioning activities · Demonstrated ability to formulate and execute meaningful scientific/clinical narratives and key messages for assets and to develop and lead the supporting evidence generation plans to close gaps, both pre and post launch · Experience developing comprehensive, cross-functionally aligned launch readiness strategies in preparation for market approvals External Engagement & Scientific Communication: · Exceptional scientific communication skills with demonstrated ability to engage and influence external stakeholders including KOLs, investigators, and scientific communities Support the acceleration of clinical trial enrollment through messaging, strategies and tactics to support clinical trial awareness and overcome barriers and through significant investigator/site engagement · Build awareness, understanding and enthusiasm for the molecule and the program through data generation, education and external engagement, with tracking record of successful thought leader engagement and advisory board leadership · Proven ability to represent the organization as a credible scientific voice at external meetings, congresses, and with professional societies · Experience translating complex scientific data into clear, persuasive narratives for diverse audiences General Responsibilities Lead and develop a team of 3-4 medical affairs professionals, providing strategic direction, mentorship, and performance management Foster a collaborative team environment that drives execution excellence and professional growth Effectively partner internally and externally to execute medical priorities Work seamlessly across the enterprise to effectively lead cross-functional initiatives Adapt quickly with the ever-changing clinical landscape and/or program priorities Effectively communicate up, down, and across the organization, and externally with scientific community and thought leaders Shape breast cancer and PI3K strategy and execution plans across the US and rest of the world Environmental Insights and Customer Engagement Understand and anticipate the scientific information needs of customers (oncologists, payers, patients, health care providers) Engage external customers through 1:1s, advisory boards, and congress-related activities Build, cultivate, and serve as primary scientific liaison with key oncology thought leaders, delivering persuasive, scientifically-grounded communications that shape clinical opinion and support disease/product awareness Contribute to the development of medical strategies to support pre- and post-commercialization activities by working closely with the Global Medical Affairs, clinical development and brand teams Identify and deliver solutions to close oncology clinical care gaps Support internal field training of medical and commercial personnel Develop and maintain appropriate collaborations and relationships with relevant professional societies Stay on the cutting edge of emerging data/science sharing key trends and data that could inform strategy Evidence Generation Identification and Action Identify evidence gaps and develop evidence generation proposals to address such Drive scientific disclosure strategy and plans Actively address customer questions in a timely fashion by leading data analyses and new clinical or health outcomes research efforts Lead the medical affairs efforts related to Innovation Readiness to shape the therapeutic landscape and clinical practice environment in preparation for Lilly's pipeline innovations, ensuring the field is primed for adoption Collaborate with clinical development to inform drug development plans and clinical trials Participate in investigator identification and selection, in conjunction with clinical development teams Support the acceleration of clinical trial enrollment through messaging, strategies and tactics to support clinical trial awareness and overcome barriers and through significant investigator/site engagement Build awareness, understanding and enthusiasm for the molecule and the program through data generation, education and external engagement Inform collaborative and investigator-initiated research (IIR) plan and publications, as requested Scientific Data Dissemination/Exchange Understand and actively address the scientific information needs of external customers in accordance with global procedures Analyze, interpret, and translate scientific data in order to generate scientific disclosures Support medical education initiatives including congress symposia, CME, and omnichannel education Review and inform medical letters, slide decks, and other medical information materials Play a leadership role in the generation of external disclosures (abstracts, posters, manuscripts) Collaborate with clinical development to support global regulatory requests (data generation, analysis, or dissemination) Offer scientific and creative input to contribute to the development, review, and approval of promotional materials for the commercial brand team Generate and deliver medical and disease state educational solutions Minimum Qualification Requirements: Medical Doctor or Doctor of Osteopathy . Must be board-eligible or certified in appropriate specialty/subspecialty or have completed the comparable level of post-medical school clinical training relevant to the country of hiring. US trained physicians must have achieved board eligibility or certification. Physicians trained outside the US who are not US board eligible or certified may be hired directly for employment in the US at the discretion of the Chief Medical Officer. Must have completed education and training at a medical school that meets the requirements of the Liaison Committee on Medical Education (LCME). For the recognized list of foreign medical schools and the disapproved list, see http://www.in.gov/pla/2799.htm Other Information/Additional Preferences : Oncology experience. Clinical research or pharmaceutical medicine experience preferred. Demonstrated ability to balance scientific priorities with business priorities. Demonstrated strong communication, interpersonal, teamwork, organizational and negotiation skills. Demonstrated ability to lead, influence, and drive alignment across cross-functional teams and with external stakeholders. Ability to travel domestically and internationally as needed to support business priorities (approximately 20-30%). Knowledge of drug development and/or medical affairs preferred. Strong understanding of US and global markets. 5 years of professional experience preferred. Fluent in English, verbal and written communication. Geographically flexible but based in the US. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $198,000 - $356,400 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. WeAreLilly

Keywords: Eli Lilly and Company, Lafayette , Senior/Executive Director Clinical Research Physician - Breast Cancer/PI3K, Science, Research & Development , Indianapolis, Indiana