Engineer - HPC Platform

Company: Eli Lilly and Company
Location: Indianapolis
Posted on: February 20, 2026

Job Description:

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Be a catalyst for innovation in high performance computing at Lilly—seize the chance to transform and accelerate our HPC future! The Cloud and Connectivity organization is seeking an engineer in HPC platforms. This role will focus on enabling analytical, statistical, and scientific computing capabilities within Lilly’s high performance computing infrastructure. We are looking for an HPC Platform Engineer to help accelerate the next era of high performance computing innovation. What You’ll Be Doing You will be a leader the engineering and operations of design, build, and maintain scalable HPC platforms. You will play a crucial role in enabling Lilly’s HPC infrastructure and experiences. Collaborate with researchers and scientists to optimize performance and streamline workflows. Leverage tooling and automation for orchestration, resource scheduling, data access, and reproducibility. Evolve and operate public cloud and on-premises environments with a focus on availability and performance for HPC workloads. Define and monitor infrastructure metrics, resource utilization, among others. How You’ll Succeed Be Bold - You will bring a high learning agility and platform engineering skills to enable the Lilly Technology strategy, identifying opportunities to accelerate our HPC journey. Be Fast - You will advance initiatives to enable critical business projects. Be Proactive - You will have opportunities to leverage agile ways of working with a willingness to become an expert in deploying HPC solutions. Be Your Best - You will learn about new technologies in HPC. What You Should Bring Hands-on experience in HPC platforms, including knowledge of accelerators (e.g., GPU), HPC schedulers (e.g., Altair Grid Engine, Slurm), Kubernetes platforms, and containers technologies (Docker, Apptainer). Demonstrated experience in HPC workloads, infrastructure, and cluster architectures. Expertise with the Linux command line, Linux troubleshooting, and HPC administration. Experience with DevOps tools such as Github, Chef, Ansible, Terraform. Experience with automating infrastructure and applications. Passion for continual learning and staying informed of new technologies, infrastructure trends, and approaches in the HPC field. Strong programming and scripting skills in languages such as Python or Bash. Basic Requirements Bachelor’s degree in computer science, Information Technology, or related technical field. 5 years’ experience HPC Platform Engineer. Demonstrated experience leading a global large-scale infrastructure project. Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1. Additional Information Hybrid role located in Indianapolis, IN (relocation required) Organization Overview Lilly IT builds and maintains capabilities using cutting edge technologies like most prominent tech companies. What differentiates Lilly IT is that we redefine what’s possible through tech to advance our purpose – creating medicines that make life better for people around the world, like data driven drug discovery and connected clinical trials. We hire the best technology professionals from a variety of backgrounds, so they can bring an assortment of knowledge, skills, and diverse thinking to deliver innovative solutions in every area of our business. The Global Information and Services Tech team is at the forefront of digitalization to enable and advance the entire company, with increased productivity and best-in-class Customer experiences. This team provides a robust and sustainable infrastructure of hardware, software and services that are critical to enable our global workforce and business to operate and transform. As leaders in technology and understanding business requirements and challenges, this team defines and leads the overall company technology strategy. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $64,500 - $184,800 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. WeAreLilly

Keywords: Eli Lilly and Company, Lafayette , Engineer - HPC Platform, IT / Software / Systems , Indianapolis, Indiana